產(chǎn)品信息 TGF-β家族成員廣泛存在于從果蠅到人多種生物的 各種組織中,對(duì)正常細(xì)胞、癌變細(xì)胞都有著顯著作用。TGF-β除了影響細(xì)胞的增殖、分化,還在胚胎發(fā)育、胞外基質(zhì)形成、 骨的形成和重建等方面起著重要作用。 LDN-193189: A selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK-2 and ALK-3). Only weakly inhibits ALK-4,-5, and -7. 4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline Ref: Cuny, G.D., et al. Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors. Bioorg Med Chem Lett 18: 4388-92, 2008. Purity: Greater than 98% as determined by LC/MS analysis. Biological Activity: Not Determined 重慶市華雅干細(xì)胞技術(shù)有限公司 |